March 13, 2026

What Biotech Gets Wrong About Commercial Sales Training

Noah Zandan
CEO & CO-FOUNDER
Blue globe displaying Africa, Europe, and parts of Asia with glowing city lights on a black background.

You just hired your 300th commercial employee. Somewhere around employee 150, you stopped contracting commercialization to a partner and started doing it yourself. Now you have a sales team. And you just realized you don't have training infrastructure.

Most biotech companies build training infrastructure wrong the first time. They hire a training person. That person inherits a role that's too broad. They're building curriculum, running onboarding, managing compliance, and coaching managers, all simultaneously. They're doing seventeen things that are actually seven separate jobs.

By year two, they're burnt out and you've got training quality issues you didn't predict.

Building training infrastructure from scratch requires thinking differently than scaling it in an established pharma company.

Why Biotech Training Usually Breaks

Biotech companies make three consistent mistakes when building commercial training:

  1. They hire a trainer instead of building a system. Most biotech companies hire their first training person and expect that person to "figure out the training." The person is talented, but they're one person managing training for a growing organization. By the time you have 300 reps, they're drowning. What should happen is: you hire someone to build the training infrastructure. That's different from hiring a trainer. That person's job is to design systems that scale, not to personally train every rep.
  2. They optimize for curriculum coverage instead of rep performance. New biotech training functions typically build comprehensive curriculum. They create modules on disease state, competitive positioning, sales skills, compliance, product knowledge. They run all reps through all modules. They measure training completion as success. Then they look at field performance and it's mediocre. They have 300 trained reps and only 40% are hitting quota. They were optimizing for what they could measure (training completion) instead of what actually mattered (rep performance). Not every rep needs the same training. Your star rep doesn't need the same confidence-building that your struggling rep needs.
  3. They wait too long to implement manager coaching. Young biotech companies focus on rep training. They get reps trained, send them to the field, and then realize that field performance depends on manager coaching. But by then, they've hired 20 managers who have no coaching discipline. Retraining managers is harder than training reps. You're asking them to change how they work. They're busy. They're skeptical. What should happen is: before you have 200 reps, you build manager coaching discipline. You train your managers to coach effectively. You measure it. You hold them accountable.

What Good Training Infrastructure Actually Accomplishes

At scale (2,000+ reps), your training infrastructure should:

  • Get reps field-ready in 10-14 weeks. From hire to independent selling. That means curriculum that's focused on what reps need to perform, not comprehensive coverage of everything.
  • Deliver 2x engagement compared to previous tools. If you started with eLearning or generic training, moving to structured simulation should increase engagement. Reps should be spending more time on training because it's more engaging and more useful.
  • Enable manager coaching at scale. Managers should have visibility into where coaching is needed and structured playbooks for delivering it. One manager should be able to coach 25-30 reps effectively.
  • Compress certification. You should measure training efficiency. How long does it take a rep to reach certification? In a well-designed system, that should be fast (10-12 minutes of actual training time per rep).

Most biotech companies don't achieve this because they're building training infrastructure while scaling at the same time. You can't afford to redesign training every six months.

How to Build It Right

If you're a biotech company with 100-300 reps and you're starting to think about training infrastructure:

Phase 1: Define Your Core Curriculum (Months 1-2)

You don't need 50 modules. You need 5-7 core modules that every rep needs:

  • Product knowledge for your portfolio (disease state, mechanism, trial data, patient selection)
  • Consultative selling skills (how to structure a call, identify need, build a case for your drug)
  • Positioning (how you're different from alternatives and why it matters)
  • Call planning and territory strategy
  • Compliance and safety

Everything else is optional. Some reps might need deeper knowledge in a particular area. That's fine. Make it available but don't force it.

Phase 2: Build Certification, Not Just Training (Months 2-4)

Training is doing something. Certification is proving competency. You need to know when a rep is actually ready to call on a physician.

Your certification should measure:

  • Can the rep articulate the unmet medical need?
  • Can the rep explain your mechanism of action accurately?
  • Can the rep handle the top three objections they'll encounter?
  • Does the rep understand appropriate patient populations?

Measure these through simulations and assessments. Don't measure "completed module X." Measure "passed assessment Y."

Phase 3: Implement Manager Coaching (Months 4-6)

Before you have 300 reps, institute manager coaching discipline:

  • Every manager coaches every rep at least monthly.
  • Coaching is structured around specific competencies, not ad-hoc.
  • You track coaching frequency and quality.
  • You hold managers accountable for coaching consistency.

This matters more than you think. Field performance depends on manager coaching more than on initial training.

Phase 4: Onboard Your Training Organization (Months 6-12)

By now you have 200-250 reps and you're adding more every week. You need to formalize your training function:

  • Hire a training director (not just a trainer). Someone who understands systems and scaling.
  • Build curriculum and assessment libraries that scale.
  • Implement a training platform that can handle growing volume.
  • Document your training process so it doesn't depend on one person.

Phase 5: Optimize (Months 12+)

Now you can measure and improve:

  • How fast are reps ramping?
  • What percentage are hitting quota in month three?
  • Are your top reps coming from your trained cohorts or from partner hires?
  • Where are reps struggling?

Use data to iterate. Maybe your curriculum needs adjustment. Maybe your manager coaching is weak in a specific area. Maybe your certification is too easy or too hard.

What to Avoid

  • Don't build comprehensive curriculum. Build focused curriculum that teaches what reps need to perform.
  • Don't hire a trainer and hope. Hire someone to build systems.
  • Don't optimize for completion. Optimize for performance.
  • Don't wait on manager coaching. Start with your first cohort of managers.
  • Don't measure training activity. Measure rep competency and field performance.

The Scaling Timeline

Building training infrastructure from scratch is a 12-18 month project. You won't get it all right the first time. That's fine. Build Phase 1-2 in the first 6 months. Iterate based on what you learn. By month 18, you should have a foundation that scales.

Where to Start

If you have 100+ commercial reps and you haven't built formal training infrastructure:

  • Month 1: Audit your current approach. What are you doing well? What's broken?
  • Month 2: Define your core curriculum. Don't try to build 50 modules. Build five.
  • Month 3: Pick your certification approach. How will you measure competency?
  • Month 4: Implement your first cohort training. Run your first 50 hires through formal onboarding.
  • Month 6: Evaluate. What worked? What didn't? Iterate.

By month 12, you'll have training infrastructure that works. It won't be perfect, but it'll be better than building ad-hoc and learning through mistakes at scale.

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